Saturday, April 111, 2018
1:00pm – 5:00pm
ISPE Board of Directors Meeting
Willow Center
Sunday, April 112, 2018
7:00am – 6:00pm
Registration
Dominion Foyer
Sunday, April 112, 2018
8:00am – 12:00pm
Introduction to Pharmacoepidemiology
Dominion South
Brief overview of course:
This half-day course will provide participants with a short introduction to the basic principles and concepts of pharmacoepidemiology. The course includes lectures on cohort studies, case-control studies, and bias & confounding.
Educational Objectives:
- Explain common study designs used in pharmacoepidemiology and appreciate their strengths and weaknesses.
- Describe the key steps in the design and analysis of cohort and case-control studies.
- Understand the major types of biases that threaten the validity of pharmacoepidemiologic research (confounding, selection bias, measurement bias).
Target Audience:
- Attendees who are new to pharmacoepidemiology or those who want a succinct refresher of the field's core concepts.
Course Faculty/Presentations:
- Almut Winterstein, FISPE, University of Florida College of Pharmacy, Cohort Studies
- Anton Pottegård, Clinical Pharmacology and Pharmacy, University of Southern Denmark, Case-Control
- Tobias Gerhard, FISPE, Ernest Mario School of Pharmacy, Rutgers University, Bias & Confounding
Presenters:
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Gerhard, Tobias
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Liu, Geoffrey
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Pottegaard, Anton
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Winterstein, Almut
Sunday, April 112, 2018
8:30am – 12:00pm
2018 Scientific Program Committee Meeting
Dominion North
Sunday, April 112, 2018
12:00pm – 1:30pm
Lunch on your own
Sunday, April 112, 2018
1:30pm – 5:30pm
Advanced Topics Course: Self-controlled Crossover Observational Pharmacoepidemiology (SCOPE)
Dominion North
Overview of Course:
Self-controlled Crossover Observational PharmacoEpidemiologic (SCOPE) study designs are “trigger designs” that control for time-invariant confounding factors, and target the association between transient exposures and sudden-onset outcomes. Causal understanding of the exposure-outcome under study is critical to selecting the appropriate SCOPE design and analysis.
This half-day course starts from first principles, and using case examples, we review outcome-anchored (case-crossover [CCO], case-time control [CTC], case-case-time control [CCTC]) and exposure-anchored (exposure-crossover [ECO], self-controlled case-series [SCCS] and self-controlled risk interval [SCRI]) study designs. Key methodological features related to exposure, outcome and confounding will be covered, and a common language and recommended approach to creating SCOPE study design figures will be introduced. The focus will be on foundational understanding to help in the design and analysis of a new SCOPE study; yet knowledge gained will also facilitate critical appraisal of published or proposed SCOPE study applications.
Educational Objectives:
Upon completing this course, participants will be able to:
- Contrast the relative strengths and limitations of SCOPE study designs;
- Use a worksheet to help inform the design of a new SCOPE study given a specific exposure, outcome and dataset;
- Create study figures to clearly summarize reasoning and methods used in a SCOPE study; and
- Calculate effect measures for SCOPE study designs.
Presenters:
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Cadarette, Suzanne
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Delaney, Jopseph
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Hallas, Jesper
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Maclure, Malcolm
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Redelmeier, Don
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Whitaker, Heather
Sunday, April 112, 2018
5:30pm – 7:30pm
Welcome Reception
Waterfall Garden
Monday, April 113, 2018
7:30am – 5:00pm
Registration
Dominion Foyer
Monday, April 113, 2018
8:15am – 9:15am
Continental breakfast/Exhibits
Dominion South
Monday, April 113, 2018
9:15am – 9:30am
Welcome and Opening Remarks
Dominion North
Monday, April 113, 2018
9:30am – 10:30am
Exploring Data and Communicating Results using Modern Data Visualization Tools
Dominion North
M. Alan Brookhart, University of North Carolina at Chapel Hill
Presenters:
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Brookhart, M. Alan
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Cadarette, Suzanne
Monday, April 113, 2018
10:30am – 11:30am
Marginal Structural Models: Nuts, Bolts and Why You Care
Dominion North
Robert W. Platt, McGill University
Presenters:
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Cadarette, Suzanne
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Platt, Robert
Monday, April 113, 2018
11:30am – 11:55am
Refreshment Break/Exhibits/Poster Viewing
Dominion South
Monday, April 113, 2018
12:00pm – 1:00pm
Quasi-Experimental Designs: Ins, Outs and Why Policy Makers Love Them
Dominion North
Linda Levesque, University of Toronto
Presenters:
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Cadarette, Suzanne
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Levesque, Linda
Monday, April 113, 2018
1:00pm – 2:00pm
Lunch/ Exhibits/Poster Viewing
Dominion South
Monday, April 113, 2018
2:00pm – 3:30pm
Student Oral Session 1 (6 talks)
Dominion North
Presenters:
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Abrahami, Devin
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Donnan, Jennifer
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Martinez, Ashley
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Montastruc, Francois
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Scotina, Anthony
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Wong, Lindsay
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Zullo, Andrew
Monday, April 113, 2018
3:30pm – 4:00pm
Refreshment Break/Exhibits/Poster Viewing
Dominion South
Monday, April 113, 2018
4:00pm – 5:30pm
Student Oral Session 2 (6 talks)
Dominion North
Presenters:
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Crispo, James
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Giannakeas, Vasily
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Hoa, Sabrina
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Matreja, Prithpal
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Smith, Amelia
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Walker, Venexia
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Whitney, Bridget
Monday, April 113, 2018
5:30pm – 5:45pm
Closing Remarks
Dominion North
Monday, April 113, 2018
6:00pm – 11:00pm
Student Meet & Greet
The Ballroom - 145 John Street
Tuesday, April 114, 2018
7:30am – 8:30am
Continental breakfast/Exhibits/Posters
Dominion South
Tuesday, April 114, 2018
7:30am – 12:00pm
Registration
Dominion Foyer
Tuesday, April 114, 2018
8:30am – 8:45am
Precision Oncology and Pharmacoepidemiology for All Ages
Dominion North
Introduction to Interactive Scenario-based Panel Symposium
Tuesday, April 114, 2018
8:45am – 9:30am
Scenario 1: Biomarker Research with the Epidemiologist in an Anchoring Role
Dominion North
Speaker and Panelists:
Rayjean Hung, University of Toronto
Amalia Issa, University of the Sciences in Philadelphia
Anke-Hilse Maitland van der Zee, University of Amsterdam
Presenters:
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Hung, Rayjean
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Issa, Amalia
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Maitland van der Zee, Anke-Hilse
Tuesday, April 114, 2018
9:30am – 10:15am
Scenario 2: Does the Host Matter? Observational Studies of the Host-Tumor Relationship
Dominion North
Speaker and Panelists:
Paul Boutros, Ontario Institute for Cancer Research
Andrew Freedman, National Cancer Institute USA
Kelly Filipski, National Cancer Institute USA
Presenters:
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Boutros, Paul
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Filipski, Kelly
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Freedman, Andrew
Tuesday, April 114, 2018
10:15am – 11:00am
Refreshment Break/Exhibits/Posters
Dominion South
Tuesday, April 114, 2018
11:00am – 12:00pm
Scenario 3: Impacting Pediatric Practice Today through Precision Oncology
Dominion North
Speakers and Panelists:
Bruce Carleton, University of British Columbia
Peter Adamson, University of Pennsylvania, Children's Oncology Group
Wei Zhou, FISPE, Merck Research Laboratories
Gillian Bartlett, McGill University
Presenters:
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Adamson, Peter
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Bartlett, Gillian
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Carleton, Bruce
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Zhou, Wei
Tuesday, April 114, 2018
12:00pm – 12:45pm
Scenario 4: Analytical Methods to Study Complex Cancer Toxicity Phenotypes
Dominion North
Speakers and Panelists:
Wei Xu, University of Toronto
Geoffrey Liu, Princess Margaret Cancer Centre
David Miller, UCB Pharmaceuticals
Presenters:
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Liu, Geoffrey
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Miller, David
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Xu, Wei
Tuesday, April 114, 2018
12:45pm – 1:00pm
Closing Remarks & Adjournment
Dominion North
